1. The Manhattan Project (1942–1946)
The Manhattan Project was a secret U.S. initiative during World War II to develop the first nuclear weapons. Led by physicist J. Robert Oppenheimer and General Leslie Groves, it involved over 130,000 personnel and cost $2 billion (equivalent to ~$27 billion today). Key achievements included:
- Trinity Test (1945): The first nuclear detonation in New Mexico, marking the dawn of the atomic age.
- Hiroshima and Nagasaki: The deployment of “Little Boy” and “Fat Man” bombs ended WWII but sparked enduring ethical debates.
- Legacy: Established nuclear energy research and Cold War geopolitics, with lasting impacts on global security.
2. Three Gorges Dam (1994–2003)
China’s colossal hydroelectric dam on the Yangtze River is the world’s largest power station by capacity (22,500 MW). Costing ¥203 billion, it displaced 1.4 million people but revolutionized renewable energy and flood control.
3. Human Genome Project (1990–2003)
This international effort mapped all human DNA, costing $5 billion. It accelerated advancements in medicine, genetics, and biotechnology, paving the way for personalized healthcare.
4. International Space Station (ISS) (1998–Present)
A collaborative effort by 15 nations, the ISS orbits Earth as a microgravity laboratory. Costing over $150 billion, it symbolizes global cooperation in space exploration and scientific research.
5. Large Hadron Collider (LHC) (2008–Present)
CERN’s particle accelerator, spanning 27 km underground, confirmed the Higgs boson in 2012. With a $4.75 billion budget, it remains pivotal in probing the universe’s fundamental laws.
6. COVID-19 Vaccine Development (2020–2023)
A global collaboration produced vaccines in record time, with €93 billion invested. Initiatives like Operation Warp Speed demonstrated unprecedented public-private synergy.
7. Boeing 787 Dreamliner (2007–Present)
The first commercial airliner built primarily with composite materials, costing $32 billion. It revolutionized fuel efficiency and passenger comfort in aviation.
8. B-2 Spirit Stealth Bomber (1987–2000)
Northrop Grumman’s $2.1 billion-per-unit bomber introduced stealth technology, reshaping military strategy with its “low observable” design.
9. F-35 Lightning II (2006–Present)
Lockheed Martin’s $1.7 trillion program created a fifth-generation multirole fighter, integrating stealth and AI-driven systems for global air forces.
10. The Stargate Project (2025–Present)
The Most Recent Megaproject
Announced in January 2025, this $500 billion AI infrastructure venture aims to solidify U.S. leadership in artificial intelligence. Key details:
The barchart below displays the costs for each of the projects. If we use project costs as an indicator of importance it becomes clear that the F-35 Lightning II ($1.7 trillion) project is by far the most important project. Followed by Stargate at a good second place. This indicates the importance of AI today! Compared with Stargate, even the Manhattan Project becomes less significant!
- Collaborators: OpenAI, SoftBank, Oracle, and NVIDIA.
- Infrastructure: 10+ data centers, starting in Abilene, Texas (875 acres), to power advanced AI systems.
- Goals: Accelerate AI innovation, create 100,000+ jobs, and develop applications like AI-designed vaccines.
- Controversies: Critics highlight minimal long-term employment from data centers and risks of deregulated AI development.
Key References
- Manhattan Project Overview: OSTI.GOV Interactive History.
- Stargate Project Announcement: Reuters Coverage.
- Stargate Infrastructure Details: Bloomberg Report.
- Ethical Debates on AI: ABC News Analysis.
Costs

Conclusion
These projects exemplify humanity’s drive to conquer scientific, technological, and societal frontiers. While their impacts are profound, they also remind us to balance ambition with ethical responsibility—a lesson as vital today as during the Manhattan Project.